Mickey Rourke is a private detective who is rigorous, conscientious, and rule-abiding. For example, he shaves his face about every four days; sometimes, even if he's just going out to buy a pack of cigarettes, he will shave before leaving. When Mickey is hired by the comically-looking Robert De Niro to find the missing Johnny Favretto, he encounters the Voodoo priestess played by Lisa Bonet, and thus, a series of incredible and bizarre events begin to unfold one after another.