The comparison between the cast of "Judge Dee Mysteries" and its sequel sees欧阳震hua continuing in the lead male role, but the female lead has changed from郭可盈in the original series to宣萱. After her contract with TVB expired last year, Guo Ke Ying did not renew it, reportedly because she had repeatedly missed out on the Best Actress award despite being a strong contender, especially when she was highly likely to win the title of "Empress of Television" for her role in "Hotel风云". However, she lost to汪明荃. Similarly, after her contract with TVB expired, Xuan Xuan signed a new contract and continues to be heavily relied upon by TVB. Even though she hasn't finished filming "Wife Boss", TVB has already started shooting the new series "Judge Dee Mysteries" with her. Ou Yang Zhen Hua and Xuan Xuan have already successfully collaborated in "Justice Bao" and "Casino Storm", and this time their collaboration might spark some new chemistry.
In addition, in "Judge Dee Mysteries", Ou Yang Zhen Hua has three wives: Xuan Xuan, Tang Ning, and Yao Ying Ying. In contrast, in the original series, Ou Yang Zhen Hua had four wives. Apart from Guo Ke Ying being replaced by Xuan Xuan, Lu Shan and Wen Song Xian do not appear, instead replaced by Tang Ning. Despite these changes, Ou Yang Zhen Hua still enjoys considerable good fortune.
Furthermore, actors like Chen Haomin and Yang Yi do not appear in "Judge Dee Mysteries", nor does veteran actor Lu Hai Peng who played the pillow god. His role is taken over by Li Si Jie, and a new character, Chen Shan Cong, is introduced.