The nuclear genome of the glacier brings new insights.

by wchenglk2 on 2012-03-01 15:47:14

"We've been studying the Iceman for 20 years. We know so much about the places where he lived, how he died, but very little about his genetic predispositions," he told BBC News. "This is very exciting, I think it's just the start of a longer research project. We want to learn more from this data, we've only just started analysing it." Showing a reconstruction of what the glacier man may have looked like before an arrow felled him Mitochondrial DNA from the glacier mummy has already shown some clues to his origins when it was fully sequenced in 2008. Albert Zink, from the Eurac Institute for Mummies and the Iceman in Bolzano, Italy, said that the nuclear DNA study represented a huge leap forward in the broad scientific understanding of the specimen. He carried a "haplotype" that suggests his ancestors most likely came from the Middle East as the practice of farming became formalised and grew in popularity. This could indicate that the transition to an agricultural society for the Iceman's community might explain his lactose intolerance. Prof Zink said www.zhong-jian.com next-generation "becoming" sequencing technology made the analysis possible. "Whole genome sequencing allows you to get at sequences in your sample in a way that would have been impossible before. Some new clues have also emerged in what can be described as the world's oldest murder mystery: the "Iceman", whose 5,300-year-old body was discovered frozen in the Italian Alps in 1991. The full genome of the Iceman has now been published in Nature Communications. The results show: he had brown eyes, BOPP film, "O" blood type, lactose intolerance, and was predisposed to heart disease. They also show he is the first recorded case of infection by borrelia, a bacteria responsible for Lyme disease. Analysis of the unusual Iceman series of DNA also revealed he is more closely related to modern residents of Corsica and Sardinia than populations in the Alps, where he was uncovered. "These are very exciting results as they help us to draw a much more detailed picture of the genetic history of the Iceman. The nuclear DNA, generally rare and less well preserved than the DNA within the mitochondria - the cell's "power plants" - also contains DNA. Related theme articles: Website Promotion Basics Written For Beginners Not dull, but Dayton is still disappointed Website Internet Promotion Company Professional Search Engine Optimization The glacier's nuclear genome brings new insights The glacier's nuclear genome brings new insights