How to Safely Use Botulinum Toxin for Wrinkle Removal? [Principle of Botulinum Toxin for Wrinkle Removal] Botulinum toxin is a bacterial endotoxin secreted by Clostridium botulinum. It acts on the terminals of cholinergic motor nerves, antagonizing calcium ion action in some way and interfering with the release of acetylcholine from the terminals of motor nerves, causing muscle fibers not to contract, leading to muscle relaxation for wrinkle removal and beauty purposes. Demonstration of the effect of injecting botulinum toxin for frown line removal: In facial beauty, moderate to severe frown lines can be improved by injecting botulinum toxin. Thus, injecting botulinum toxin is an effective minimally invasive cosmetic method for removing facial wrinkles, worthy of choice by those seeking beauty. However, plastic surgery experts point out that although the effect of botulinum toxin for wrinkle removal is relatively ideal, not every beauty seeker can choose this method. It is necessary to consider whether the beauty seeker's physical condition allows for botulinum toxin injection to ensure the safety of beautification. For example, if the injection site for botulinum toxin exceeds the "safe zone," it may cause drooping eyebrows, ptosis, protruding eyelids, and in severe cases, fever, fatigue, and breathing difficulties may occur. Safety Precautions for Injecting Botulinum Toxin for Wrinkle Removal: 1. Effectiveness and Limitations of Botulinum Toxin for Wrinkle Removal? Effectiveness: A direct injection of botulinum toxin into the wrinkles will gradually flatten them within 3 to 14 days, with effects typically lasting 3 to 6 months. To maintain long-term effectiveness, injections are needed 3 to 4 times per year. Using botulinum toxin for wrinkle removal usually works for crow's feet, forehead lines, glabellar lines, nasal lines, and neck wrinkles but is most suitable for early, less noticeable wrinkles. Limitations: If the beauty seeker has deep wrinkles or loose skin, the results may vary. 2. What Are the Side Effects of Injecting Botulinum Toxin? After injecting botulinum toxin, symptoms such as dry mouth, headache, neck pain, or eye problems like double vision, blurred vision, decreased vision, ptosis/swelling of the eyelids, and dry eyes may occur. 3. Who Should Not Use Botulinum Toxin for Wrinkle Removal? 1. Pregnant and breastfeeding women; 2. Patients with myasthenia gravis or multiple sclerosis; 3. Patients with upper eyelid ptosis; 4. Very thin individuals with heart, liver, or kidney diseases; 5. Individuals with allergic constitutions. For pregnant or breastfeeding beauty seekers, they should carefully consider choosing botulinum toxin projects because botulinum toxin may affect fetal development. Additionally, there is no definitive scientific evidence regarding whether botulinum toxin affects breast milk health, so it is not recommended for breastfeeding women to choose injections. For beauty seekers with an allergic constitution who have an allergic reaction to botulinum toxin or have skin infections at the expected injection site, injections are not advisable. Note that severe allergic reactions after injecting botulinum toxin include redness and itching, rashes, asthma, wheezing, or dizziness. For beauty seekers with myasthenia gravis, patients with muscle atrophy or sclerosis, such as amyotrophic lateral sclerosis, myasthenia gravis, or Lambert-Eaton syndrome, if these patients undergo botulinum toxin injection, serious side effects may occur, including severe swallowing and breathing difficulties. Communication with the attending physician before injecting botulinum toxin includes discussing any medications recently taken, including over-the-counter drugs, prescriptions, vitamins, and herbal medicines. Whether other types of wrinkle products have been injected previously, along with the time and location of the injection. Finally, inform the attending physician about any recent antibiotic injections or allergies to certain drugs. [Editor’s Note] Indeed! Wrinkles are undoubtedly the "main culprit" killing youth for beauty-loving women, making wrinkle removal a focal issue for many beauty enthusiasts. Plastic surgery experts point out that aging is a natural physiological change, and wrinkles are one of the signs of aging skin. Beauty seekers should correctly recognize this beauty method. Wrinkle removal projects can improve skin wrinkles to some extent but cannot fundamentally remove wrinkles. Beauty seekers should choose appropriate wrinkle removal methods based on the severity of their wrinkles and have a correct understanding of the wrinkle removal effects. This not only effectively improves facial wrinkles but also enhances confidence!