Under the microscope, for the single nostril transsphenoidal resection of pituitary adenomas, a saline flush was used after blood. In 3 patients post-treatment: (1) postoperative nasal packing expansion sliver was applied, removed after 3 days; (2) large doses of antibiotics were used to prevent wound infection and intracranial infection; (3) appropriate supplemental hormones were administered to prevent hypopituitarism; (4) access to water was monitored for 24 hours, Abercrombie Deutschland shop, with timely correction of electrolyte disturbances and diabetes insipidus. Results showed that 18 postoperative patients recovered without complications. After a mean follow-up of 5 months (2 ~ 10), no relapse occurred. Among 6 patients with decreased visual acuity, 5 cases recovered to normal, and 1 case improved. Endocrine dysfunction in 10 patients saw menses resumption in 6 patients within 2 months, and 5 patients with acromegaly showed some reduction. Clinical investigation of hormone levels revealed 16 cases recovered to normal, and 2 cases declined. After 2 months, MRI in 15 cases showed 3 cases completely resected, partial resection discussed. Due to the minimally invasive nature of microscopic single nostril transsphenoidal resection of pituitary tumors, its advantages are evident, leading to increasing application, expanding indications, more methods, and better efficacy L2J. One, experience: 1 This operation approach retains the septum mucosa without resection, avoiding nasal mucosa atrophy and nasal septum perforation; 2 Curettage of the tumor should scrape the rear and both sides first. If the front is scraped first, it can easily cause saddle vibration sinking, cerebrospinal fluid leakage, affecting the operation's effect; 3 Resection of the tumor using different caliber curettes, from shallow to deep, repeated curettage, propulsive, avoided side injury caused by scraping; 4 Intraoperative cavernous sinus injury hemorrhage should be avoided by electric coagulation hemostasis, using gelatin sponge compression hemostasis, which shows apparent effect. Two, operation indications and contraindications: 1 Indications include: (1) a pituitary microadenoma; (2) less than 5crn in diameter portion of giant pituitary tumors, not invading the cavernous sinus on the sides. If the tumor has relatively soft texture, smooth and tidy edges, no divided leaves, it is also suitable for this operation approach because giant pituitary adenomas mostly have crispy soft tissue, making them easy to scrape and suction part, with cystic changes, only a few textures hard and tough [0]; (3) oronasal sphenoid sinus pituitary tumor resection in some patients where tumors are still in situ or growing within the sphenoid sinus due to loss of normal anatomical structure, making the oronasal sphenoid sinus approach difficult, thus endonasal transsphenoidal resection of pituitary tumor L4J line is preferred. 2 Contraindications: (1) Tumor growth significantly towards the back of the saddle, causing heavier visual acuity and visual field damage; (2) Tumor growth invading the cavernous sinus on the sides; (3) Smaller nostrils or significantly abnormal intranasal anatomical structure with sphenoid sinusitis, nasal polyps; (4) Tumor diameter greater than 5ClTI with tough texture; (5) Coagulation disorders or other serious diseases present. L5j. Three, Advantages and Disadvantages of the Operation: 1 Advantages: (1) Can completely resect tumors with soft texture not growing towards the cavernous sinus on both sides. In particular, excision of adenoma avoids the traditional transfrontal approach which may easily cause pituitary stalk injury. (2) Little injury pair, avoiding frontal, optic nerve, olfactory nerve injury during transcranial operation. Just open the sphenoid sinus to resect the tumor, not easily damaging hypothalamus and frontal tissues, reducing complications such as diabetes insipidus and psychiatric symptoms, whereas transcranial approach operations injure posterior hypothalamus making it difficult to restore L5J.