A Brief Introduction to the Secret of Penile Erection with Placenta Extract
The secret of penile erection: Male physiology involves changes in the hemodynamics of the penile corpus cavernosum under neuro-endocrine regulation. When sexually stimulated, non-adrenergic non-cholinergic neurons secrete neurotransmitters such as nitric oxide (NO). Nitric oxide enters the smooth muscle cells of the corpus cavernosum and activates guanylate cyclase, converting guanosine triphosphate into the second messenger cyclic guanosine monophosphate (cGMP). The increase in intracellular cGMP concentration leads to relaxation of the corpus cavernosum smooth muscle, causing the sinusoids of the corpus cavernosum to swell, increasing arterial blood flow, and expanding the volume of the corpus cavernosum. The tunica albuginea surrounding the corpus cavernosum passively stretches, compressing and narrowing the sub-tunical venules that drain blood from the corpus cavernosum, increasing venous outflow resistance, leading to penile enlargement and increased rigidity, resulting in an erection. As cGMP is degraded by phosphodiesterase type 5 (PDE5) within smooth muscle cells and after ejaculation when the sympathetic nervous system recovers, the penis transitions from a taut state to flaccidity.
Since PDE5 is selectively distributed in the smooth muscles of the corpus cavernosum, cGMP-specific PDE5 inhibitors are currently the preferred oral medications for treating erectile dysfunction. Intracavernosal injection of prostaglandin E1 is also used for treating erectile dysfunction, with its mechanism of action involving the activation of adenylate cyclase to synthesize cAMP, where an increase in the latter induces relaxation of the corpus cavernosum smooth muscle, triggering penile erection. Furthermore, under the mediation of adrenergic neurotransmitters, contraction of the corpus cavernosum smooth muscle cells reduces penile blood flow and opens venous return, leading to penile flaccidity. Phentolamine, an alpha-adrenergic receptor blocker, is used in intracavernosal injection therapy for treating erectile dysfunction.
Placenta extract, human placenta, human placental extract, human placental tissue fluid (placenta, Zi He Che) has a very long history in China. Historical records indicate that as early as the Qin Dynasty during the reign of Emperor Qin Shi Huang, placenta was considered an essential health supplement for the royal family. Qin Shi Huang's use of placenta was consistent with his pursuit of immortality. In folk usage, human placenta is mainly associated with "tonifying deficiencies, infertility, and enhancing male sexual function."
How do placenta extract, human placenta, human placental extract, human placental tissue fluid (Zi He Che) enhance sexual function? According to classical Chinese medical texts such as "Compendium of Materia Medica," "Supplement to the Compendium of Materia Medica," and "Modern Chinese Medical Dictionary," Zi He Che (human placenta) has the effects of "greatly tonifying vital energy, supporting the body's normal functions, replenishing the kidneys and strengthening yang, nourishing blood and filling essence, calming the mind and protecting the spirit, invigorating qi and strengthening the spleen."
Modern pharmacological studies have found that placenta extract, human placenta, human placental extract, and human placental tissue fluid (Zi He Che) are rich in various amino acids and contain abundant proteins such as albumin, globulin, macroglobulin, and multiple placental globulin antibodies. They also contain many active substances essential for human physiology and more than 55 types of enzymes necessary for human physiology, such as hyaluronidase and protein synthesis enzymes, which play a crucial role in maintaining normal endocrine function in the human body. Their significance to the human body lies in ensuring it remains in a healthy state, maintaining various bodily functions at a vigorous level, effectively improving the functional decline of various organs, delaying the decline of physiological functions, and effectively ensuring and extending the youthful state of the human body. Based on the results of pharmacological research, placenta extract, human placenta, human placental extract, and human placental tissue fluid (Zi He Che) are highly effective in treating sexual dysfunction and low sexual function. This explains why clinically, placenta extract, human placenta, human placental extract, and human placental tissue fluid (Zi He Che) are widely used and effective in treating impotence, premature ejaculation, sexual dysfunction, and male infertility.
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