The first beating heart condition valved ascending aortic replacement operation completed tract spasm and other shortcomings, limiting the clinical use. Sevoflurane is a new type of inhalation anesthetics, with a slightly sweet odor, minimal irritation to the respiratory system, and provides a comfortable inhaled feeling, making it acceptable for children to inhale. Blood gas partition coefficients are 0.63, and brain/blood distribution coefficient is 1.7, therefore inducing onset and rapid awakening. The Jiang Jundan report aspiration 4% sevoflurane lash reflex time of 1.24min, and the tests for the 1.8min, may be related to the age of children with smaller experiments, MAC relatively large. There are reports that higher concentration of inhalation induces more quickly, and the experiment results show that the ketamine group has a shorter pain vanishing time than the sevoflurane group, which may be associated with the strong analgesic effect of ketamine. The recovery time of the sevoflurane group was shorter in the ketamine group, with sevoflurane having a small distribution coefficient, making it more suitable for short operations under sevoflurane anesthesia. Burn patients experience diffusion from circulating blood to tissue interstitial fluid, reduction in circulating blood volume, and attention needs to be paid to the influence on circulation during anesthesia. It is generally believed that sevoflurane has no effect on heart rate or slightly increases it. In this experiment, the heart rate and blood pressure of the sevoflurane group were not significantly changed, therefore sevoflurane is safe for burn patients. While the ketamine group exhibits sympathetic excitatory effects and obvious rise. There have been reports that inhaling 8% sevoflurane without cough or laryngospasm occurred, and it has a small impact on respiration, whereas ketamine for pediatric lip and palate repair easily evokes laryngeal spasm. The present study of the sevoflurane group had no respiratory depression, no oxygen saturation below 95%, while the ketamine group appeared in 1 case with laryngeal spasm, requiring assisted ventilation. Description of 3% ~ 5% sevoflurane on respiratory inhibition is very small, patients can maintain spontaneous breathing, while complications are fewer than ketamine. This group of 3% sevoflurane intraoperative body case numbers in 6 cases, 3% concentration is low; 4% and 5% compared sevoflurane awakening time and on circulatory, respiratory effects have no difference, whereas 5% sevoflurane faster onset of action. To sum up, sevoflurane has onset and rapid awakening, small effects on circulatory and respiratory systems, children are easy to accept, and reduces a lot of the incidence of complications, applied in 4, JL burn dressing change and short operation anesthesia, with 5% sevoflurane effect is good.