Sodium nitroprusside and dopamine, furosemide in treating acute left heart failure # 183; min) increased gradually, dose adjustment, at the same time light. In group C, group A on the basis of conventional therapy, combined with sodium nitroprusside 25mg, dopamine 40mg, 40mg with frusemide in 5% glucose solution 500ml IV drip, 15, 30min were measured before and after treatment of respiratory, heart rate, blood pressure, oxygen saturation (SaO), ECG changes and symptoms and signs. Efficacy of 1.3 standards: effect: use 15 ~ 30min dyspnea, palpitations, chest pain or significant relief, no sweat, no cough and hemoptysis of frothy sputum, no irritability, urine amount, respiration, blood pressure, can lie, heart rate, SaO obvious change for the better, don't significantly reduced lung sound; effective: medication 15 ~ 30min dyspnea and palpitations, chest pain and symptom relief, cough and hemoptysis of frothy sputum reducing improvement, cyanosis, desirable semi recumbent, blood pressure, heart rate, fast, SaO: improved pulmonary hiccup sound, partially reduced; invalid: use L5 ~ 30min, heart failure symptoms, signs, blood pressure, SaO unchanged, even heavier or death. At the same time the observation of adverse drug reaction. 1.4 statistics: the determination value mean value and standard deviation of 177 #; (& # 177; s), statistical analysis, statistical analysis to (2) test and t test. 2 Results 29 cases in A group: 7 cases (24.1%), effective in 13 cases (44.9%), invalid in 9 cases (31%), the total effective in 20 cases (69%). 29 cases in B group: 18 cases (62.1%), effective in 8 cases (27. 6%), invalid in 3 cases (10.3%), the total effective in 26 cases (89.7%). 29 cases in C group: 25 cases (86.2%), effective in 3 cases (10.3%), invalid in 1 cases (3, 4%), the total effective in 28 cases (96. 5%). The total efficiency of A group compared with B group P 0.05, the process of treatment, no obvious adverse reaction. Discussion of acute left heart failure patients 3 as emotional, sympathetic activation vasoconstriction, arterial blood pressure is elevated, if the original hypertension, blood pressure will be higher, this time combined with sodium nitroprusside in the treatment of lower blood pressure, and increased cardiac index, lower pulmonary artery wedge pressure, rapid relief of symptoms, significant curative effect. But some patients with the disease progress, especially in patients with acute myocardial infarction, blood pressure often decline, serious person can appear in cardiogenic shock, this time should not be applied to sodium nitroprusside treatment, 3 cases in group B ineffective treatment patients, including 2 cases of acute myocardial infarction, will belong to such a situation. Group C patients application of sodium nitroprusside and dopamine in treatment of solves the problems existing in the B group therapy. Because dopamine has a positive inotropic effect, can be excited P. Receptor, activation of adenylate cyclase, increase the content of CAMP in myocardial tissue, enhance myocardial contractility, increased cardiac output, at the same time can be selectively dilated renal vasodilation, increased renal blood flow, have diuresis effect. The drug combination can make use of sodium nitroprusside on peripheral vascular dilatation function reduce heart before, after load, using dopamine enhanced myocardial contractility, keep blood pressure stable, ensure the important organ blood supply. Therefore, the combination can produce synergistic and complementary effect. Applies to both hypertension and low blood pressure of the patients, but also suitable for application of digitalis in heart failure patients. The study of sodium nitroprusside in the treatment of acute left heart failure effect is remarkable, and furosemide dopamine, in effect, more safety. Application of drug of attention when correction of electrolyte and acid-base balance, for relief of symptoms after disabling, along with ACEI, receptor blockers in the treatment of.