Pyrethroid pesticide poisoning report of 43 cases: dosage ranged from OOO - 3ooo ml/day. Treatment included Nei Jiawei raw cable C, adrenal cortex shock Faso, Glucurolactone, energy mixture, and in some cases, furosemide and mannitol. Seizures were controlled with stability and LO ~ 2O mg intravenously. Disease eight received atropine O.5 ~ LO mg intravenously, with attention to electrolyte balance, control of senses, oxygenation, and symptomatic treatment. All 43 cases were cured, with 15 hospitalized for three days and 28 hospitalized for up to 7 days.
Discussion results align with literature and treatment experience:
① Clearing the poison to prevent continued entry into the body. Timely washing of skin contact areas, gastric lavage with water or sodium bicarbonate was administered early on. Among the 30 festering wounds treated within 45 hours, good results were achieved.
General clinical data: 30 cases below, 45 wounds. Men: 18 cases, 30 planing surfaces; Women: 12 cases, 15 profiles; average age of 56.5 years. Age range: 38 to 75 years, average wound area 5.2cm, maximum area 5x15cm, minimum area lxlcm. Bacterial cultures of wounds showed Staphylococcus Miao in 18 cases, Gram-negative bacteria in 12 cases. Pathological examination of tissue sections revealed variability of inflammatory cells. Affected parts included both legs and toes in 30 cases, neck and back in 1 case, fingers in 3 cases. Thirty patients had their wounds closed by only one voltage graft, while the rest healed naturally.
Drug sleeve composition and medication use: Chinese medicine ingredients include Cork, Calcitum, etc., Western medicine includes sulfadiazine zinc and its slander agent Azone. Planing surface was first washed repeatedly 2 to 3 times with 3% hydrogen peroxide solution and normal saline, necrotic crusts were cut off, and single-layer sterile gauze dipped in creams was placed under the section size, semi-exposed or bandaged with gauze, replaced every 3 days.
Efficacy Results: After the first application of medication, secretions increased as necrotic tissue dissolved and gradually reduced. Three to five days after planing, secretions decreased, necrotic tissue cleaned around the profile, inflammation subsided, fresh granulation tissue or skin continued to change dressings, forming islands. Granulation planing surface epithelial tissue crawled inward from the profile periphery, less than 2 ~ 3cm deep. Outside diameter caliper measurement showed an average daily growth of o25mm in 10 such profiles, approaching normal skin speed at 0.27rura1. Planing surface island formation rate was 21%.
Treatment accompanied by large doses of Vit C, liver protection drugs, and increased glucocorticoid energy agents to protect nerves and other internal organs function, alleviate and prevent cerebral edema. Antibiotics cord was applied to prevent infection. Convulsions and irritability were controlled with 1O mg intravenously, repeated if necessary every l ~ 2 hours, yielding good results. Diuretics and mannitol 250 ml intravenous injection were given for cerebral edema, and oxygen inhalation was provided for difficulty in breathing or cyanosis. All cases used small doses of atropine 0.5 to 10 mg intravenously, achieving better results. Atropine not only resists pyrethroids caused salivation but also alleviates total poisoning symptoms by blocking acetylcholine at M receptors, preventing continuous bronchial and glandular secretion, reducing body fluid loss, and avoiding fatal airway obstruction. However, excessive use should be avoided to prevent aggravating the condition. Atropine solidly inhibits gastric emptying, intestinal motility, and intestinal fluid secretion, extending toxic effects.
Treatment principles for other mixed pesticide poisoning should be based on clinical manifestations, different pesticide products' slow action, granulation tissue edema, secretions, and bacterial culture negative rate over a long time. Ulcers flat cream's negative rate was higher one week later, reaching about 20%. Four typical cases included a 52-year-old female with primary diabetes for 20 years, left leg inner skin ulcers for 18 years, chronic diseases, planing weeks showing obvious inflammatory infiltration canine-like. Secretions were thin, red, more in amount, surrounding skin was purple calm, ulcerated area approximately 5 x 15cm, urine +}. Wound bacterial culture showed S. aureus. Admitted on January 25, 1994, simultaneously applying diabetes control drugs, ulcers flat cream dip gauze sticking profiles were OK, semi-exposed. Five days after, necrotic tissue dissolved clean, reducing secretions, granulation tissue and loose skin island formed. One week later, bacterial culture showed overcast records, peripheral inflammatory infiltration significantly diminished. Gradual growth was organized in 12 days, and semi-profile healed in 3 weeks.
Ulcers Ointment is a paste mixture of Chinese and Western medicine with resistance to infection. Clinical observation shows it dispels rotten tissue, regenerates, including blood addiction, promotes blood circulation, quickly gets rid of necrotic tissue, creating good conditions for epithelial tissue growth. This group of drugs, with penetration enhancers like Azone (Chongqing, China Biochemical Technology Co., Ltd.), allows profile vasodilator, increases permeability, and zinc ions promote epithelial growth after treatment, keeping the wound warm and moist, conducive to the protection of ecological organization. Jiaozuo lH layer hospital treated 4541s1 child solder Lei foot with this method.