First trimester fetal intrauterine growth restriction: Clinical analysis of 12 cases from Nanmedical College for Staff and Workers. Pregnancy complications, tobacco, cheap Beats by Dre, alcohol, and the impact of certain drugs were considered. Within this group, there was no clear reason for growth restriction in 12 cases of embryo development. Given HCG, progesterone, and to correct luteal phase defect, Si Lian, vitamin E, and other micronutrient supplementation, along with nourishing the endometrium, allowed the embryo to continue developing. We believe that during early gestation, the embryo at a certain stage may be affected by some unknown internal and external factors that limit its growth and development or even cause stagnation, which is still worth further investigation. This group of patients suggests that in clinical practice, if menopause lasts 6-8 weeks and B-mode ultrasound yet fails to show fetal heartbeat, one should consider the possible existence of fetal intrauterine growth restriction, especially in patients with long-term infertility. These patients should be closely observed and continued tocolytic treatment under the expectation of a normal fetus.