-80 ℃ two freeze-dried pig skin for second-degree burn wounds

by wrefsprqc on 2012-02-07 16:05:30

-80 ℃ two freeze-dried pig skin is used to the improvement of the II degree burn wound dressing method onicVersion ~ June2oQ, V0,: 0.182, P> 0.50, therefore the two groups were comparable. Two. Methods: fresh take small healthy white domestic pig skin, shaving routine cleaning the Shanghai Kai Li instrumentarija, production electric take Paper Machine to fat, the skin made into two parts, namely, the upper 0.4 ~ 0 .6 mm edge thickness skin graft, for the removal of the lower epidermis and the fat layer of the pig two thin skin. Clinical application, two groups of wounds are 0.05% chlorhexidine acetate (ie, chlorhexidine) liquid debridement, removal of the blisters on the skin and separation of the epidermis. Group A: a 80c Superficial Ⅱ degree wound outer layer of dressing dry, you can package to heal; deep II degree burn wound in about 4 days to open the outer layer of dressing, check the absence of subcutaneous effusion melting pig skin, the infection, you can simply replace the outer dressing layer, continue to pay deposited; if the pigskin has begun to dissolve, then re-debridement, the replacement of pigskin. Group B: All wounds were topical 10% SD-Ag cream, as the wound dressing every 13. Superficial Ⅱ degree burn wound healing time in group A, the earliest 8d, 12d at the latest; group B of the first 10d, at the latest 14d; deep second degree burn wound healing time in group A the first 18d 23d at the latest; group B is the first 21d, the latest 27d,ugg pas cher, the average value in Table 1. Table 1 two sets of wound healing time (days, ± s) Note: The M-test, superficial second degree burn wound between the two groups, M: 8.73, P <0.01; deep Ⅱ degree burn wound between the two groups and u: 6.33, P <0.01, the results have significant differences. Discussion 1. Traditional burn wound topical application of SD-Ag cream cross deposited anti-infective, because of its strong irritant of the wound, pain, need to alleviate the continuous 1 ~ 2h, some patients will be pain; sulfa allergy careful , ? delayed deep II degree burn wound re-epithelialization of the phenomenon. Two freeze-dried pig skin, has good toughness and wear resistance, and the wounds healed without irritation, therefore, can better protect the wound to avoid patients grasp, rub and damage the wound, susceptible patients, especially in burn s ~ JL accepted. Two. In the preparation of pigskin process, only the blade made of thick pigskin after repeated fat reserves used in clinical surgery and dressing, applies to take the rest of the middle-free epidermis and the fat layer of large two pigskin discard]. Through clinical trials show that the two this layer of pig skin as a biological covering, can effectively prevent the excessive evaporation of surface water, so that the wounds to maintain an appropriate temperature, shallow wound, is conducive to the growth of epithelial cells and promote wound healing. 3. Pig two leather easy to expose in addition, non-irritating, low-cost characteristics for small and medium size mixing Ⅱ degree burns, especially in patients with financial difficulties, and provide a good way of dressing. 4. Two, freeze-dried pig skin is best used for a cleaner burn wounds, and severe wound contamination or suspected infection, the outer cover porcine dermis and then apply a layer of sterile gauze (such as 0.5% of the available iodine content povidone-iodine or 0.05% chlorhexidine acetate wet gauze) dressing the J. 5 Experiments show that the lyophilized pig skin is used to light two, deep partial thickness burn wounds in the control group compared with the traditional sD-Ag cream was significant difference (P <0.01). In addition to the pig epidermis, retain their dermal layer, and thus help to reduce the incidence of patients with late scarring and deformity, and reduce dressing change the number to alleviate patient pain, shorten wound healing time, reduce hospitalization costs, reduce the workload of medical staff In particular, the promotion to the grass-roots hospitals.