The initial symptom of acute leukemia is mostly fever, which can be expressed as a patent fever, continued fever, intermittent fever or irregular fever. Anemia is often the first symptom of leukemia, and is mainly manifested as pallor, weakness, powerlessness and hyperhidrosis (excessive sweating). If parents find that their children have anemia, feel weak all over the body, look very pale, have unexplained fever or bleeding, they should immediately take the child to the hematological specialty department of a hospital for examination.