Diphenoxylate hydrochloride and dl - 15 methyl PGF2α methyl ester in rat ovarian luteal... National Academy of Medical Sciences 1989; 9:65.2. JaffeJH. Narcotic analgesics. In: GoodmanLS and GilmanA, ghd piastra, eds. 4th ed ● 1 | } ■ specifically The Pharmacological Basis of Therapeutics ● ● the Qiang pharmacy of Acta Pharmaceutica Simca 1991; 26 (12): 886~889889 New York: MacMillan, l97l: 258.3. The king of selenium successful. A 15-methyl prostaglandin F2 methyl merger application of hydrochloric acid phenethyl piperidine study the role of anti-early pregnancy in the rat. Chinese Academy of Medical Sciences 1989; 9:414.4. SufiSB, ata1. Programme for the Provision of Matched Assay Reagents for the Radioimrrunoassay of Hormones in Reproductive Physiology. 6th ed. Geneva: WHO, north face sale, 1982:67.5. WangNG, eta1. Effects of gossypol acetic acid oil on luteal cells plus vitro. Ethnopharmacology. 1987; 20:45. EFFECTS OF DIPHENOXYLATE HYDROCHLORIDE AND a 15 METHYL PROSTAGLANDIN F2 . c METHYL ESTER ON RAT LUTEAL CELLS ● NGwang, Moncler Online, MZGuan and XCZuo (Institute of Materia Medica, ghd prezzi, Chinese Academy of Medical Sciences, Be # mg100050) ABSTRACT Diphenoxylate hydrochloride (Rll32) at concentrations of 10 and 20 # g / ml or d / a l5methyl - PGF methylester (PG05) at levels of 5 and 10 / ~ g / ml was shown to have no effect on progesterone secretion by luteal cells in vitro in the absence of hCG. A marked increase in progesterone level was elicited by hCG as high as 3 ~ 8fold the original value. The steroidogenic response of luteal cells to hCG was inhibited by R1132 and PG05, Rl132 at a daily dose of 10mg/kg or PG05 at a daily dose of 0.1mg/kg for 5 days showed no obvious effect on ovary progesterone secretion in pseudopregnant rats. However, moncler soldes, treatment with R1132 10mg/kg plus PG05 0.1mg/kg resulted in a decrease in the progesterone production of ovaries in vitro. R1132 and PG05 at doses of 50mg/kg and 0.5mg/kg, respectively, exhibited an inhibitory effect on the adenylate ~ cyclase activity. Keywords Diphenoxylate hydrochloride; d / a l5 Methyl - PGF2 a methyl ester; Luteal cells; Adenylate cyclase