Tylosin biosynthesis and fermentation. 15:84; (CA1987, 107:114189) [823 (Czech1987.240342); CA1989.110: 230182 [83] (PCTIntAppl, 8400777); CA1984, l groan: 178170sr84] MasumaRetahFermentTechno [19881:607; (CA1984.1 groan: 99 619) [85] OmuraSetal: AdvBiotechnol (PreIntFermentSymp) 6th. The 80.3:181 r36_SaitoBet81: ShokuhlnEis ~ igakuZ the ~ shi1983, 7.4:130: (CA1988.9 ~: 619 501 [8 knife NeidertEetal: JAssoco ! wire f..’’ dark. 70197 [41] (FreidlinPJ: AvianDis1988.3Z: 370) ~ cAf3SenoETetal:. ~ mtimicrobialAgents & of Che moth1977, 11:455 [39] (TyaglovBVeta1: Biotekhnologiya19 ship. '= 648): CA1988. 109:168868 [40] (HoshinoYetal: ShokuhlnEi ~ igakuz & s3hi1984.75: 490): CA1985102: 666l988.109: 125778 [42] (IonovaIetal: Vet MedN ~ uki1988.22: 7B); CA1986.104: 1472881 [ ,],[strain improvement, ugly income gather in harvest fermentation technology in September [1990] ● pharmaceutical microbial fermentation production of elastase Yanzi Ying Kwan Kwok-hung (Guangzhou Pharmaceutical Industrial Research Biochemistry, Guangzhou 51924 Baiyunshan Pharmaceutical Factory of Biological Chemistry, Guangzhou) Abstract This paper reviews the application microbial production of elastase profiles, combined with the work of the author’s outlook to pull the yeast method to replace the organ extraction method of production of the medicinal enzyme feasibility and superiority. Keywords microbial the divinatory yeast elastase medicinal production of elastase (elastase) as the treatment of hyperlipidemia, effective biochemical drugs for prevention and treatment of atherosclerosis has been widely used medicinal elastase production in China is mainly extracted from pig pancreas, but the supply of resources, limiting the expansion of production of the drug abroad has been prepared by microbial fermentation reported. In this paper, intended as an introduction to related research profile, the medical value of elastase and the distribution of the 1949 Balo isolated from pancreatic extracts can be specific hydrolysis insoluble elastin protein, proteolytic enzyme - elastase (pancreatic endopeptidase E), and pointed out that a lot of research work related to the occurrence of atherosclerosis and the enzyme before the ancient amount. that the enzyme can be used for the treatment of hyperlipidemic disease, arterial atherosclerosis. early 8O, the enzyme has been listed as drugs. elastase such as animal pancreas, aorta, platelets, white blood cells of skin, etc. there are also elastin hydrolytic activity in microorganisms There are also widely distributed microbial strain with the secretion of extracellular elastase capacity is mainly distributed in the following seedlings is: More articles related to topics:
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