Mona Lisa [Edit This Section] The Mystery of Mona Lisa's Smile For 500 years, people have been divided on the mysterious smile of "Mona Lisa". Different observers or those who view her at different times seem to have varying feelings. Sometimes she appears to smile gently and warmly, sometimes she seems serious, sometimes slightly sad, and at other times even sarcastic and teasing. In a painting, changes in light cannot produce as significant differences as they do in sculptures. However, on Mona Lisa's face,