Cell line identity authentication

by weixingds on 2009-08-07 14:34:43

Human Cell STR Genotyping Service (Cell Line Identity Authentication)

Cell contamination and misidentification are very common, which can have a significant impact on subsequent research, especially in the fields of stem cell and tumor cell research. According to statistics, 15%-25% of research papers have incorrect conclusions due to the use of misidentified or cross-contaminated cells. Therefore, monitoring for contamination and mutations is crucial. STR genotyping of cell lines is a fast, cost-effective, and highly accurate method for identifying contaminated or misidentified cells. Internationally, it has become a routine means of cell authentication, with ATTC containing STR genotyping data for each cell line.

Features:

(1) Highly informative, analyzing more than 15 STR loci simultaneously, enabling accurate determination of cross-contamination and cell type;

(2) High sensitivity, capable of detecting as low as 0.1ng DNA (approximately 15 diploid genomes), allowing detection of trace contamination;

(3) High-throughput and systematic platform, with a daily processing capacity of over a thousand tests, using an automated software analysis system for data analysis and comparison.

Applicable Scope:

• Users who utilize human-derived cell lines for research and production, including but not limited to the following fields: medicine, genetics, drug development, vaccine research and development, biotechnology and pharmaceutical industries, regenerative medicine, basic science, HIV detection and treatment, and cell biology.

• Major cell repositories

• Peer review for scientific journals

• Academic organizations

• Government departments and private institutions