Premenstrual discomfort is a set of symptoms experienced by women who suffer from periodic premenstrual discomfort that suddenly disappears at the onset of menstruation. These symptoms typically appear around 10 days before menstruation and include physical symptoms such as fatigue, headache, backache, breast pain, pelvic discomfort, cramping abdominal pain, and edema, as well as mental symptoms such as emotional agitation and anxiety. During physical examinations, signs such as breast fullness and tenderness, slight enlargement and sensitivity of the uterus, and increased secretions from the cervix and nasal cavity may be observed, but there are no signs of infection. Clinically, the various symptoms of premenstrual discomfort described above are generally referred to as premenstrual syndrome (PMS).