The inducements of achromia can be dozens of kinds, such as great stress, emergency situations, trauma, decreased immunity, endocrine disorders, relative lack of tyrosine and copper ions, heredity, infection and so on. It is currently considered that the Koebner phenomenon is a kind of autoimmune phenomenon. In the statistics of 904白癜风 patients, 127 cases (14.1%) had the Koebner phenomenon induced by various reasons, which aggravated the condition of white spots.