Many middle-aged and elderly people have the habit of exercising in the morning. However, early morning is the peak time for cardiovascular events, which may be related to the sudden increase in blood pressure after waking up in the morning, accelerated heart rate, increased platelet aggregation, reduced fibrinolytic activity, and enhanced activity of the sympathetic nerve.
This requires clinical doctors to provide all-day antihypertensive protection when prescribing antihypertensive drugs, with particular attention to controlling morning blood pressure. However, research shows that among patients whose clinic blood pressure is under control, about 60% of them do not have their morning blood pressure under control. Therefore, hypertensive patients should pay attention to measuring their blood pressure upon waking up. It is recommended to measure between 6-9 am, which represents the morning blood pressure value. Studies have found that cardiovascular events such as myocardial infarction, cardiac sudden death, and stroke (hypertension complications) occur with a clear diurnal variation pattern, especially between 6 am and 10 am or noon, when the incidence is highest.
High daytime blood pressure is associated with the risk of death from cerebral infarction; high nighttime blood pressure is associated with the risk of death from hemorrhagic stroke and cerebral infarction; while elevated morning blood pressure is significantly associated with total cerebrovascular events, hemorrhagic stroke, cerebral infarction, and the risk of death from ischemic heart disease.
To avoid excessively high morning blood pressure, there are mainly three treatment options: using long-acting and potent antihypertensive drugs; changing the medication time to before sleep; and taking antihypertensive drugs with a timed-release system.
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