Arteriosclerotic obliterans is a common and frequently-occurring disease. In 1891, Von Mantenfel first discovered that arteriosclerotic occlusion could lead to limb necrosis. Since then, with the improvement of detection methods and the development of vascular surgery, there has been a deeper understanding of arteriosclerotic obliterans, and better therapeutic effects have been achieved in treatment.
Arteriosclerotic obliterans is a degenerative lesion and the basic pathological process of large and medium arteries, mainly characterized by abnormal deposition of cells, fibrous matrix, lipids, and tissue debris, causing hyperplasia in the arterial intima or middle layer.