Coagulation experiment on standardization and quality control includes several suggestions. Laboratory quality control mainly involves precision, linear range comparison, and anti-interference testing. During the evaluation of instruments, operators can become familiar with operational methods, while simultaneously verifying the correctness of new determination methods. Before establishing standard curves for routine specimen determinations involving 22 instruments, when replacing reagent batches, or after instrument repairs, it is necessary to re-establish the standard curve.
For indoor quality control, ensuring precision is essential. Laboratories that meet certain conditions are encouraged to use quality control substances. For laboratories without complete quality control substances, they may choose quality control substances matching their instrument principles, calibrate them to fixed values, and then develop indoor quality control processes.
Through external quality assessment activities (2.4), improvements in laboratory determination result comparability can be achieved. Solidified laboratories should participate in quality assessment activities that include parameters such as Prothrombin Time (Pr), Activated Partial Thromboplastin Time (APTT), and Fibrinogen (Flag). Determination results outside the normal reference range (25) require special attention. It is crucial to correctly understand the concept of normal reference values. Normal values are not simply fixed ranges prescribed by operating procedures or textbooks but vary depending on factors such as the apparatus, reagents, age, gender, and environmental conditions. Therefore, equipment operators should learn how to determine normal reference values according to different actual situations.